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Journal of Applied Veterinary Sciences
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Issue Issue 1
Ibrahim, H., Mohammed, G., Shell, W., Sayed, M., El-Sadek, G. (2016). Efficacy of an experimental E. coli inactivated vaccine in turkey poults. Journal of Applied Veterinary Sciences, 1(1), 7-14. doi: 10.21608/javs.2016.61820
Hazim Ibrahim; Gina M. Mohammed; W.S. Shell; M.S. Sayed; Ghada M. El-Sadek. "Efficacy of an experimental E. coli inactivated vaccine in turkey poults". Journal of Applied Veterinary Sciences, 1, 1, 2016, 7-14. doi: 10.21608/javs.2016.61820
Ibrahim, H., Mohammed, G., Shell, W., Sayed, M., El-Sadek, G. (2016). 'Efficacy of an experimental E. coli inactivated vaccine in turkey poults', Journal of Applied Veterinary Sciences, 1(1), pp. 7-14. doi: 10.21608/javs.2016.61820
Ibrahim, H., Mohammed, G., Shell, W., Sayed, M., El-Sadek, G. Efficacy of an experimental E. coli inactivated vaccine in turkey poults. Journal of Applied Veterinary Sciences, 2016; 1(1): 7-14. doi: 10.21608/javs.2016.61820

Efficacy of an experimental E. coli inactivated vaccine in turkey poults

Article 2, Volume 1, Issue 1, October 2016, Page 7-14  XML PDF (498.5 K)
Document Type: Original Article
DOI: 10.21608/javs.2016.61820
View on SCiNiTO View on SCiNiTO
Authors
Hazim Ibrahim1; Gina M. Mohammed2; W.S. Shell2; M.S. Sayed2; Ghada M. El-Sadek2
1Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo, Egypt
2Central Laboratory for Evaluation Veterinary Biologics, Abbasia, Cairo, Egypt.
Receive Date: 22 July 2016,  Revise Date: 25 November 2019,  Accept Date: 15 August 2016 
Abstract
E. coli infections are responsible for great economic losses in the poultry industry worldwide, bringing serious threat to the turkey industry. The present investigation aimed to prepare a potent vaccine from E. coli serogroups O1 and O78 to aid in control of colibacillosis in turkey. One hundred commercial 14 days-old turkey poults were used and divided into three groups; first group was vaccinated twice with 3 weeks interval by prepared inactivated E.coli vaccine adjuvanted with aluminum hydroxide gel, second group was vaccinated twice with 3 weeks interval by prepared inactivated E.coli vaccine adjuvanted with montanide ISA70, third group was left as unvaccinated control one. The immune response was measured by MAT (Microagglutination test), ELISAand challenge test. It was found that the protection rate for inactivated vaccine with aluminum hydroxide gel and E.coli inactivated vaccine with montanide ISA70 were 80% and 85%  respectively although it was 30% among the unvaccinated group.
Keywords
inactivated vaccine; E. coli; ELISA; MAT
Main Subjects
Poultry diseases
References
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